Humans ‘Very Likely’ Responsible for Warming, Report Concludes

Food Taxes: How Likely Are Likely Effects?

Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.

To clarify the UDP-glucuronosyltransferase (UGT) isoform(s) responsible for the glucuronidation of the thyroid hormone thyroxine (T(4)) in the human liver, the T(4) glucuronidation activities of recombinant human UGT isoforms and microsomes from seven individual human livers were comparatively examined. Among the 12 recombinant human UGT1A and UGT2B subfamily enzymes examined, UGT1A1, UGT1A3, U...

Mechanisms responsible for sympathetic activation by cigarette smoking in humans.

BACKGROUND The pressor and tachycardic effects of cigarette smoking are associated with an increase in plasma catecholamines, suggesting the dependence of these effects on adrenergic stimulation. Whether the stimulation occurs at a central or a peripheral level and whether reflex mechanisms are involved is unknown. METHODS AND RESULTS In nine normotensive healthy subjects (age, 33.0 +/- 3.5 y...

Open Abdomen Management and Candida Infections: A Very Likely Link

Objective Laparostomy can be applied in trauma, abdominal sepsis, intra-abdominal hypertension, or compartment syndrome. Systemic infections, especially if complicated by Candida, are associated with a high risk of mortality. Methods This is a single-centre retrospective case series of 47 cases admitted to our Department, which required laparostomy procedure; we analyzed the type of surgery, ...

Audit concludes Infoway missed program targets.

© 2011 Canadian Medical Association or its licensors CMAJ, May 17, 2011, 183(8) 893 years ago, it began requiring codes of conduct as a condition of hospital accreditation. The codes have to define acceptable, disruptive and inappropriate behaviours, Schyve says, adding that the purpose of such codes is to encourage a culture of safety, where people feel free to report adverse events, close cal...